Clinical Profile of Indoor Covid-19 Patients at a Medical Institute In India: A Retrospective analysis

Authors

  • Mariyam Khwaja Integral Institute of Medical Sciences and Research, Integral University, Lucknow
  • Deeapk Chopra Integral Institute of Medical Sciences and Research, Integral University, Lucknow https://orcid.org/0000-0001-5779-5818
  • Pankaj Kumar Verma Integral Institute of Medical Sciences and Research, Integral University, Lucknow https://orcid.org/0000-0002-7473-9639
  • Nidhi Jauhari Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow
  • Shadiya Shehnaz Integral Institute of Medical Sciences and Research, Integral University, Lucknow

DOI:

https://doi.org/10.47203/IJCH.2022.v34i02.030

Keywords:

Clinical, Epidemiological, SymptomsClinical, Clinico-Epidemiological Profile, COVID 19, Symptoms

Abstract

Background: COVID-19 has caused a very high burden of morbidity and mortality across the world, India being  also badly affected. The disease has a wide spectrum ranging from asymptomatic to severe illness and death. Research work on the epidemiological and clinical profile of patients is scarce in India. Objectives: This study was conducted to know the clinico-epidemiological profile of indoor hospitalized Covid 19 patients. Methods: a retrospective analysis (record based) conducted at a designated COVID tertiary care center. Study period-1st August 2020 to 31st October 2020. Study Unit- Laboratory confirmed COVID 19 patients admitted in the hospital. Sample size- All the 894 patients with complete record were included in the study. Results: The mean age was 47.68± 17.62 years. Around 14.1% of the population was asymptomatic. 75.7%  were classified as having a mild disease. The cure rate was 82.9% and deaths were reported in 9.4%. Conclusions: Our findings were similar to findings observed in other studies. A positive significant correlation was noticed between age, duration, clinical severity and outcome of patient. The clinical severity was also found to be associated with age, duration of symptoms and outcome of patient 

Downloads

Download data is not yet available.

References

Timeline?: WHO ’ s COVID-19 response [Internet]. 2020. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/interactive-timeline?gclid=CjwKCAjw74b7BRA_EiwAF8yHFInemP1BDiiAwHTrCmC28nxhTSTvEckCV8pkWTz9Ye5sX1RST90i7BoCfdEQAvD_BwE#event-115 accessed on 25.06.2022

World Health Organization. Coronavirus Disease (COVID-19) [Internet]. Vol. Coronaviru. 2020. Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200907-weekly-epi-update-4.pdf?sfvrsn=f5f607ee_2 accessed on 25.06.2022

Coronavirus outbreak in India [Internet]. 2020. Available from: https://www.covid19india.org/state/UP accessed on 25.06.2022

CDC. Symptoms of Coronavirus | CDC [Internet]. Centers For Disease Control and Prevention. Available from: https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html accessed on 25.06.2022

Fu L, Wang B, Yuan T, Chen X, Ao Y, Fitzpatrick T, et al. Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis. J Infect [Internet]. 2020;80(6):656–65.

Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–20.

Chen Q, Zheng Z, Zhang C, Zhang X, Wu H, Wang J, et al. Clinical characteristics of 145 patients with corona virus disease 2019 (COVID-19) in Taizhou, Zhejiang, China. Infection [Internet]. 2020;48(4):543–51.

Zhang J jin, Dong X, Cao Y yuan, Yuan Y dong, Yang Y bin, Yan Y qin, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy Eur J Allergy Clin Immunol. 2020;75(7):1730–41.

Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, Villamizar-Peña R, Holguin-Rivera Y, Escalera-Antezana JP, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Med Infect Dis [Internet]. 2020;34(March):101623. Available from: https://doi.org/10.1016/j.tmaid.2020.101623 accessed on 25.06.2022

Ministry of Health and Family Welfare. CLINICAL MANAGEMENT PROTOCOL?: COVID-19. Version 3 [Internet]. 2020. Available from: https://www.mohfw.gov.in/pdf/ClinicalManagementProtocolforCOVID19.pdf accessed on 25.06.2022

Gupta N, Agrawal S, Ish P, Mishra S, Gaind R, Usha G, et al. Clinical and epidemiologic profile of the initial COVID-19 patients at a tertiary care centre in India. Monaldi Arch Chest Dis. 2020;90(1):193–6.

Mohan A, Tiwari P, Bhatnagar S, Patel A, Maurya A, Dar L et al. Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. Indian J Med Res. 2020 Jul & Aug;152(1 & 2):61-69. doi: 10.4103/ijmr.IJMR_1788_20. PMID: 32773414; PMCID: PMC7853260.

Sun Y, Koh V, Marimuthu K, Ng OT, Young B, Vasoo S, et al. Epidemiological and Clinical Predictors of COVID-19. Infect Dis Soc Am. 2020;71(15):786–92.

Cao Z, Li T, Liang L, Wang H, Wei F, Meng S, et al. Clinical characteristics of Coronavirus Disease 2019 patients in Beijing, China. PLoS One [Internet]. 2020;15(6):1–7. Available from: http://dx.doi.org/10.1371/journal.pone.0234764 accessed on 25.06.2022

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting Characteristics, Comorbidities, and Outcomes among 5700 Patients Hospitalized with COVID-19 in the New York City Area. JAMA - J Am Med Assoc. 2020;323(20):2052–9.

Kronbichler A, Kresse D, Yoon S, Lee KH, Effenberger M, Shin J Il. Asymptomatic patients as a source of COVID-19 infections: A systematic review and meta-analysis. Int J Infect Dis [Internet]. 2020;98:180–6. Available from: https://doi.org/10.1016/j.ijid.2020.06.052 accessed on 25.06.2022

Badawi A, Ryoo SG. Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis. Int J Infect Dis [Internet]. 2016;49(January):129–33. Available from: http://dx.doi.org/10.1016/j.ijid.2016.06.015 accessed on 25.06.2022

Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. J Immunol. 2017;198(10):4046–53.

Jaillon S, Berthenet K, Garlanda C. Sexual Dimorphism in Innate Immunity. Clin Rev Allergy Immunol. 2019;56(3):308–21.

Wan S, Xiang Y, Fang W, Zheng Y, Li B, Hu Y, et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. J Med Virol. 2020;92(7):797–806.

Sherwal BL, Makkar N, Jain A, Dogra V, Prasad S, Sachan A, et al. Trends and clinico ? epidemiological profile of COVID ? 19 patients at a designated COVID ? 19 hospital in Delhi , North India. 2020;6261–6.

Yang W, Cao Q, Qin L, Wang X, Cheng Z, Pan A, et al. Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China. J Infect [Internet]. 2020;80(4):388–93.

Qian GQ, Yang NB, Ding F, Ma AHY, Wang ZY, Shen YF, et al. Epidemiologic and clinical characteristics of 91 hospitalized patients with COVID-19 in Zhejiang, China: a retrospective, multi-centre case series. QJM An Int J Med. 2020;113(7):474–81.

Asghar MS, Haider Kazmi SJ, Ahmed Khan N, Akram M, Ahmed Khan S, Rasheed U, et al. Clinical Profiles, Characteristics, and Outcomes of the First 100 Admitted COVID-19 Patients in Pakistan: A Single-Center Retrospective Study in a Tertiary Care Hospital of KarachiCorrection. Cureus. 2020;12(6): e8712.

Jin X, Lian JS, Hu JH, Gao J, Zheng L, Zhang YM, et al. Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms. Gut. 2020;69(6):1002–9.

Tan WYT, Wong LY, Leo YS, Toh MPHS. Does incubation period of COVID-19 vary with age? A study of epidemiologically linked cases in Singapore. Epidemiol Infect. 2020;148:1–6.

CDC. COVID-19 Increased Risk of Hospitalization or Death Age Increases Risk for Severe Illness Age Increases Risk for Hospitalization. 2021.

CMO. Discharge Policy for COVID 19 patients. Lucknow; 2020

Downloads

Published

2022-06-30

How to Cite

1.
Khwaja M, Chopra D, Verma PK, Jauhari N, Shehnaz S. Clinical Profile of Indoor Covid-19 Patients at a Medical Institute In India: A Retrospective analysis. Indian J Community Health [Internet]. 2022 Jun. 30 [cited 2024 Jul. 3];34(2):311-6. Available from: https://iapsmupuk.org/journal/index.php/IJCH/article/view/2319

Issue

Section

Short Article