Validity of point-of-care device for diagnosing anemia in workers exposed to lead

Published

2022-12-31

DOI:

https://doi.org/10.47203/IJCH.2022.v34i04.023

Keywords:

Lead, Point-of-Care Systems, Occupational Health, Hemoglobin, Anemia

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Issue

Section

Short Article

Authors

  • Ankit Viramgami Indian Council of Medical Research - National Institute of Occupational Health, Ahmedabad, Gujarat https://orcid.org/0000-0002-1519-7948
  • Soundarya Soundarajan Health Science Division, Indian Council of Medical Research - National Institute of Occupational Health, Ahmedabad, Gujarat https://orcid.org/0000-0003-0383-8389
  • Ankit Sheth Health Science Division, Indian Council of Medical Research - National Institute of Occupational Health, Ahmedabad, Gujarat
  • Kuldip Upadhyay Indian Council of Medical Research - National Institute of Occupational Health, Ahmedabad, Gujarat

Abstract

Detecting anemia in occupational health settings is critical in a high-risk population for anemia like the lead-exposed. Whether the point-of-care devices are sensitive to detect anemia in individuals with high levels of lead exposure is unknown. We compared hemoglobin (Hb) levels from HemoCue® Hb 301 System and standard analyzer, Mindrey-BC 5300, in individuals (n=58) exposed to lead (mean levels = 44.9 ?g/dL) for a chronic period (mean duration of exposure = 105 months). We observed high sensitivity (0.95), specificity(0.95) in detecting anemia by hemocue, and high agreement between the methods. The significant difference in Hb values between the methods (0.171g/dL, p=0.018) was clinically minimal. We conclude that hemocue is a good method for rapidly detecting anemia and estimating Hb levels among the lead-exposed in resource-limited settings.

How to Cite

1.
Viramgami A, Soundarajan S, Sheth A, Upadhyay K. Validity of point-of-care device for diagnosing anemia in workers exposed to lead. Indian J Community Health [Internet]. 2022 Dec. 31 [cited 2023 Feb. 6];34(4):573-6. Available from: https://iapsmupuk.org/journal/index.php/IJCH/article/view/2489

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References

Marcus, H., C. Schauer, and S. Zlotkin, Effect of Anemia on Work Productivity in Both Labor- and Nonlabor-Intensive Occupations: A Systematic Narrative Synthesis. Food Nutr Bull, 2021. 42(2): p. 289-308.

Oppenheimer, S.J., Iron and its relation to immunity and infectious disease. J Nutr, 2001. 131(2s-2): p. 616S-633S; discussion 633S-635S.

Wangping, J., et al., Associations Between Anemia, Cognitive Impairment, and All-Cause Mortality in Oldest-Old Adults: A Prospective Population-Based Cohort Study. Front Med (Lausanne), 2021;8:613426.

Didzun, O., et al., Anaemia among men in India: a nationally representative cross-sectional study. Lancet Glob Health, 2019;7(12):e1685-e1694.

Bhatia, V., et al., A Community based Study of Anaemia Burden using Hemocue 201 in Eastern India. Indian Journal of Community Health, 2020. 32(2).

Roshania, R.P., et al., Agreement between dried blood spots and HemoCue in Tamil Nadu, India. Sci Rep, 2021. 11(1):9285.

Geneva, S. and W.H. Organization, Haemoglobin concentrations for the diagnosis of anemia and assessment of severity. Vitamin and Mineral Nutrition Information System. Document Reference WHO. 2011, NMH/NHD/MNM/11.1. http://www. who. int/entity/vmnis/indicators/haemoglobin.

Team, R., RStudio: integrated development environment for R. RStudio. Inc., Boston, MA, 2015. 14.

McBride, G., A proposal for strength-of-agreement criteria for Lin's concordance correlation coefficient. Hamilton, New Zealand: National Institute of Water & Atmospheric Research Ltd; 2005. 2005.

Power, M., G. Fell, and M. Wright, Principles for high-quality, high-value testing. Evid Based Med, 2013. 18(1):5-10.

Gwetu, T., et al., Hemocue validation for the diagnosis of anemia in children: a semi-systematic Review. Pediat Therapeut. 2013; 4(1): 1-4.