COVID-19 causes more mortality of men than women, why and how? Scientists view

Abstract

As of August 6, 2020, 15;46 GMT COVID -19 cases were 19,062,200 and deaths were 712,741(1). Since the inception of Covid-19, countries around the world are reporting the mortality rate of COVID-19 is significantly higher in men than it is in women. In almost all countries where data is available, it appears men are dying at a higher rate once infected with COVID-19 (2). Research suggests that mast cells in women are able to initiate a more active immune response, which may help them fight infectious diseases better than men. Initial reports from China revealed the early evidence of increased male mortality associated with COVID. According to the Global Health 50/50 research initiative, nearly every country is now reporting significantly higher COVID-19-related mortality rates in males than in females as of June 4 (3). As regards sex of the first deaths reported by the China National Health Commission (NHC) a review was done. The NHC reported the details of the first 17 deaths up to 24 pm on January 22, 2020. The deaths included 13 males and 4 females (4). According to the WHO Situation Report no. 7 issued on Jan. 27,71% of cases were male. (5)