A Hospital based cross sectional study to find out factors associated with disease severity and length of hospital stay in COVID-19 patients in Tertiary Care Hospital of Ahmedabad city
DOI:
https://doi.org/10.47203/IJCH.2021.v33i02.006Keywords:
COVID-19, Disease Severity, Length of Stay, OutcomeAbstract
Background: Tertiary hospital care may vary from isolation bed ward care to high dependency units (HDUs) with oxygen support to intensive care unit (ICU) where patients may be intubated for mechanical ventilation The major risk factors for severe disease are age more than 60 years and underlying diseases like diabetes, hypertension. COVID-19 patients present at varying levels of severity. Understanding how long patients hospitalized with COVID-19 remain in hospital is critical for planning. Objectives: 1. To determine risk factors associated with disease severity 2. To determine risk factors associated with length of hospital stay in COVID-19 patients 3. To study the disease outcome Material & Methods: This was retrospective record-based study of inpatients with COVID-19 at Tertiary Care Hospital of Ahmedabad City. All patients admitted at tertiary care hospital diagnosed with COVID-19 between April 2020 to June, 2020, were included in present study. Inclusion criteria were all COVID-19 patients admitted at tertiary care hospital during the duration of April 2020 to June 2020. Results: A total of 916 COVID-19 patients were included in the study. Out of 916 total admitted patients 526 (57.4%) were male. 174 (19%) patients having one or more comorbidities like diabetes, hypertension, tuberculosis, heart diseases etc. Total 769 discharged (83.9%), 115 deaths (12.6%) and 32 transferred to other COVID-19 hospital (3.5%) out of total 916 patients admitted during study period. Conclusion: Severity of disease and deaths were associated with age and comorbidities. COVID-19 patients with comorbidities have more deteriorating outcomes compared with patients without.
Downloads
References
Post COVID Management Protocol Background.; 2020.
COVID-19 advice - Know the facts | WHO Western Pacific. Accessed March 13, 2021. https://www.who.int/westernpacific/emergencies/covid-19/information/severity
WHO-2019-nCoV-Surveillance_Case_Definition-2020.2-eng.
Tenforde MW, Kim SS, Lindsell CJ, et al. Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network — United States, March–June 2020. MMWR Morbidity and Mortality Weekly Report. 2020;69(30):993-998. doi:10.15585/mmwr.mm6930e1
Americans L. Being a current or former cigarette smoker increases the risk for severe illness from COVID-19. 1 Non-Hispanic American Indians and Alaska Natives ? People of multiple races Both smoking and COVID-19 disproportionately impact racial, ethnic, and sexual minority groups. 5,6. doi:10.15585/mmwr.mm6924e2
(No Title). Accessed March 16, 2021. https://www.mohfw.gov.in/pdf/UpdatedClinicalManagementProtocolforCOVID19dated03072020.pdf
Jiang F, Deng L, Zhang L, Cai Y, Cheung CW, Xia Z. Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19). Journal of General Internal Medicine. 2020;35(5):1545-1549. doi:10.1007/s11606-020-05762-w
Cascella M, Rajnik M, Cuomo A, Dulebohn SC, di Napoli R. Features, Evaluation and Treatment Coronavirus (COVID-19). StatPearls Publishing; 2020. Accessed March 17, 2021. http://www.ncbi.nlm.nih.gov/pubmed/32150360
Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Medicine and Infectious Disease. 2020;34:101623. doi:10.1016/j.tmaid.2020.101623
Thiruvengadam G, Lakshmi M, Ramanujam R. A Study of Factors Affecting the Length of Hospital Stay of COVID-19 Patients by Cox-Proportional Hazard Model in a South Indian Tertiary Care Hospital. Journal of Primary Care & Community Health. 2021;12:215013272110002. doi:10.1177/21501327211000231
Wu Z, McGoogan JM. Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases from the Chinese Center for Disease Control and Prevention. JAMA - Journal of the American Medical Association. 2020;323(13):1239-1242. doi:10.1001/jama.2020.2648
Dong Y, Dong Y, Mo X, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145(6). doi:10.1542/peds.2020-0702
Stokes EK, Zambrano LD, Anderson KN, et al. Coronavirus Disease 2019 Case Surveillance — United States, January 22–May 30, 2020. MMWR Morbidity and Mortality Weekly Report. 2020;69(24):759-765. doi:10.15585/mmwr.mm6924e2
Rees EM, Nightingale ES, Jafari Y, et al. COVID-19 length of hospital stay: A systematic review and data synthesis. BMC Medicine. 2020;18(1):270. doi:10.1186/s12916-020-01726-3
Undurraga EA, Chowell G, Mizumoto K. COVID-19 case fatality risk by age and gender in a high testing setting in Latin America: Chile, March–August 2020. Infectious Diseases of Poverty. 2021;10(1):11. doi:10.1186/s40249-020-00785-1
Biswas M, Rahaman S, Biswas TK, Haque Z, Ibrahim B. Association of Sex, Age, and Comorbidities with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Intervirology. 2021;64(1):36-47. doi:10.1159/000512592
Barek MA, Aziz MA, Islam MS. Impact of age, sex, comorbidities and clinical symptoms on the severity of COVID-19 cases: A meta-analysis with 55 studies and 10014 cases. Heliyon. 2020;6(12):e05684. doi:10.1016/j.heliyon.2020.e05684
Vahidy FS, Pan AP, Ahnstedt H, et al. Sex differences in susceptibility, severity, and outcomes of coronavirus disease 2019: Cross-sectional analysis from a diverse US metropolitan area. Lazzeri C, ed. PLOS ONE. 2021;16(1):e0245556. doi:10.1371/journal.pone.0245556
Berlin DA, Gulick RM, Martinez FJ. Severe Covid-19. Solomon CG, ed. New England Journal of Medicine. 2020;383(25):2451-2460. doi:10.1056/NEJMcp2009575
Wu S, Xue L, Legido-Quigley H, et al. Understanding factors influencing the length of hospital stay among non-severe COVID-19 patients: A retrospective cohort study in a Fangcang shelter hospital. Serra R, ed. PLOS ONE. 2020;15(10):e0240959. doi:10.1371/journal.pone.0240959
Vulnerable populations. Accessed April 3, 2021. http://www.bccdc.ca/health-professionals/clinical-resources/covid-19-care/clinical-care/vulnerable-populations
Anderson MR, Bach PB, Baldwin MR. Hospital Length of Stay for Patients with Severe COVID-19: Implications for Remdesivir’s Value. 2021;5:129-131. doi:10.1007/s41669-020-00243-6
Chen F-J, Li F-R, Zheng J-Z, et al. Factors associated with duration of hospital stay and complications in patients with COVID-19. Journal of Public Health and Emergency. 2021;5(0):6-6. doi:10.21037/jphe-20-74
Wang D, Li R, Wang J, et al. Correlation analysis between disease severity and clinical and biochemical characteristics of 143 cases of COVID-19 in Wuhan, China: A descriptive study. BMC Infectious Diseases. 2020;20(1):519. doi:10.1186/s12879-020-05242-w
Downloads
Published
How to Cite
License
Copyright (c) 2021 Indian Journal of Community Health
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.