Goitrogens And Goitre— A Clinicosocial Study Of Association

Abstract

Research Problem : Is there any role of goitrogens in the causation of goitre? Objectives :    (1)     To describe the intake of goitrogenic substances in goitrous and non-goitrous patients. (2) To find out the types and frequency of goitrogenic subtanccs in these patients. Study Design : Hospital-based Study by Questionnaire Method. Setting : Endocrinology Out Patients Department, J.N.Medical college Hospital, A.M.U., Aligarh. Participants : Cases were patients having clinical features of iodine deficiency disorders (IDD) and controls were not having goiter but they had other endocrinological disorders in the Endocrinology O.P.D. at J.N. Medical College Hospital, A.M.U., Aligarh. Study variables : Intake, type and frequency of goitrogenic substances. Outcome variables : Percentage of goitrous and nongoitrous patients consuming goitrogenic substances. Statistical Analysis : Chi-Square Test. Result : In goitrous patients, a dietary' history' of goitrogen intake was found in 93.85% patients while in nongoitrous patients, it was 76.92%, Commonly consumed vegetables having goitrogenic properties were Cabbage, Cauliflower and Lady’s finger. Intake was frequent (once a week) in most of the goitrous patients while it was taken occasional (once fortnightly) in most of the nongoitrous patients. Conclusion : Majority of the goitrous patients were consuming goitrogenic substances. Their role in the causation of goiter is clearly understood. However, for this further research activities should be carried out to find out the strength of association.