A study on predictors of treatment outcome among children registered under DOTS in district Tarn Taran, Punjab






Tuberculosis, Children, Predictors, Treatment outcome

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Original Article


  • Pooja Sadana Sri Guru Ram Das Institute of Medical Sciences and Research, Sri Amritsar https://orcid.org/0000-0002-0694-3718
  • Vishal Verma Tarn Taran, Punjab
  • Manisha Nagpal Sri Guru Ram Das Institute of Medical Sciences and Research, Sri Amritsar


Background: Globally, tuberculosis remains an important cause of morbidity and mortality for children. Diagnosis and management of childhood TB especially Extra pulmonary tuberculosis is challenging. Method:  A cross-sectional study was conducted on 0-14 year children who were registered and being treated, in district Tarn Taran, Punjab from 1st January 2018 to 31st December 2018. The treatment outcome with their clinico-demographic determinants was ascertained. Data management and analysis was done by using Microsoft excel and SPSS. Results: Out of 62 registered patients, 62.9% of the children were in age group of 11-14 years. 67.7% were females. The various treatment outcomes observed were-cured 32.3%, treatment completed 61.3%, lost to follow up 1.6%, regimen changed 1.6%, not evaluated 3.2%. The success rate (cured+ treatment completed) was 93.6%. On statistical analysis, it was observed that age (p= 0.002), site of disease (p=0.000), contact history (p=0.012) and diagnostic method (0.000) was significantly associated with the treatment outcome whereas gender, area of residence and type of case had no association with the treatment outcome in children. Conclusions:  We also found that the overall treatment success rate was 93.6%. Increased focus be on those with household contact with TB.

How to Cite

Sadana P, Verma V, Nagpal M. A study on predictors of treatment outcome among children registered under DOTS in district Tarn Taran, Punjab. Indian J Community Health [Internet]. 2020 Jun. 30 [cited 2023 Mar. 24];32(2):399-403. Available from: https://iapsmupuk.org/journal/index.php/IJCH/article/view/1539


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WHO. Global tuberculosis report 2018. Available at https://www.who.int/tb/publications/global_report/en/

Dodd PJ, Yuen CM, Sismanidis C, Seddon JA, Jenkins HE. The global burden of tuberculosis mortality in children: a mathematical modelling study. Lancet Glob Health. 2017 Sep;5(9):e898-e906. doi: 10.1016/S2214-109X(17)30289-9. PubMed PMID: 28807188; PubMed Central PMCID: PMC5556253.[PubMed]. doi: 10.1016/S2214-109X(17)30289-9.

WHO. Roadmap towards ending TB in children and adolescents. Geneva: World Health Organization 2018. Available at https://apps.who.int/iris/bitstream/handle/10665/274374/9789241514668-eng.pdf Accessed on 11/3/ 2020.

Thomas TA. Tuberculosis in Children. Pediatr Clin North Am. 2017 Aug;64(4):893-909. doi: 10.1016/j.pcl.2017.03.010. Review. PubMed PMID: 28734517; PubMed Central PMCID: PMC5555046.[PubMed].

Cowger TL, Wortham JM, Burton DC. Epidemiology of tuberculosis among children and adolescents in the USA, 2007-17: an analysis of national surveillance data. Lancet Public Health. 2019 Oct;4(10):e506-e516. doi: 10.1016/S2468-2667(19)30134-3. Epub 2019 Aug 21. PubMed PMID: 31446052.[PubMed].

John TJ. Tuberculosis control in India: why are we failing?. Indian Pediatr. 2014 Jul;51(7):523-7. doi: 10.1007/s13312-014-0440-x. PubMed PMID: 25031127.[PubMed].

Revised National Tuberculosis Control Programme. Training Course for medical officers and TB program managers. Modules 1-4: Central TB Division, Directorate General of Health Sciences, Ministry of Health and Family Welfare, New Delhi. 2019:152.

Hailu D, Abegaz WE, Belay M. Childhood tuberculosis and its treatment outcomes in Addis Ababa: a 5-years retrospective study. BMC Pediatr. 2014 Mar 3;14:61. doi: 10.1186/1471-2431-14-61. PubMed PMID: 24581267; PubMed Central PMCID: PMC3944801.[PubMed].

Tilahun G, Gebre-Selassie S. Treatment outcomes of childhood tuberculosis in Addis Ababa: a five-year retrospective analysis. BMC Public Health. 2016 Jul 21;16:612. doi: 10.1186/s12889-016-3193-8. PubMed PMID: 27443308; PubMed Central PMCID: PMC4957362.[PubMed].

Bharani A, Harshey M, Raipurkar S. Profile and outcome of childhood tuberculosis treated with DOTS at a tertiary care hospital in central India: an observational study. Int J Contemp Pediatr. 2018; 5: 324-7.

Marais BJ, Hesseling AC, Gie RP, Schaaf HS, Enarson DA, Beyers N. The bacteriologic yield in children with intrathoracic tuberculosis. Clin Infect Dis. 2006 Apr 15;42(8):e69-71. doi: 10.1086/502652. Epub 2006 Mar 6. PubMed PMID: 16575719.[PubMed].

Planting NS, Visser GL, Nicol MP, Workman L, Isaacs W, Zar HJ. Safety and efficacy of induced sputum in young children hospitalised with suspected pulmonary tuberculosis. Int J Tuberc Lung Dis. 2014 Jan;18(1):8-12. doi: 10.5588/ijtld.13.0132. PubMed PMID: 24365546.[PubMed].

Mazta SR, Kumar A, Kumar P. Demographic Profile of Childhood TB Cases under Revised National Tuberculosis Control Program in Himachal. Bangalore: National Tuberculosis Institute Bulletin. 2014. http://tbresearch.ntiindia.org.in/id/eprint/1628.

Dhaked S, Sharma N, Chopra KK, Khanna A, Kumar R. Socio-demographic profile and treatment outcomes in pediatric TB patients attending DOTS centers in urban areas of Delhi. Indian J Tuberc. 2019 Jan;66(1):123-128. doi: 10.1016/j.ijtb.2018.06.006. Epub 2018 Jul 12. PubMed PMID: 30797269.[PubMed].

Laghari M, Sulaiman SAS, Khan AH, Memon N. A prospective study of socio-demographic, clinical characteristics and treatment outcomes of children with tuberculosis in Sindh, Pakistan. BMC Infect Dis. 2019 Jan 24;19(1):82. doi: 10.1186/s12879-019-3702-3. PubMed PMID: 30678656; PubMed Central PMCID: PMC6345030.[PubMed].

Ogbudebe CL, Adepoju V, Ekerete-Udofia C, Abu E, Egesemba G, Chukwueme N, Gidado M. Childhood Tuberculosis in Nigeria: Disease Presentation and Treatment Outcomes. Health Serv Insights. 2018;11:1178632918757490. doi: 10.1177/1178632918757490. eCollection 2018. PubMed PMID: 29511357; PubMed Central PMCID: PMC5826094.[PubMed].

Laghari M, Sulaiman SAS, Khan AH, Memon N. Epidemiology of tuberculosis and treatment outcomes among children in Pakistan: a 5 year retrospective study. PeerJ. 2018;6:e5253. doi: 10.7717/peerj.5253. eCollection 2018. PubMed PMID: 30065869; PubMed Central PMCID: PMC6065458.[PubMed]

Ramesh, Shobha A, Manjula VD. Treatment Outcomes of Childhood Tuberculosis with Dots Strategy in Kottayam, Kerela. Indian J Community Health. 2012; 24(4):280-4.

Alavi SM, Salmanzadeh S, Bakhtiyariniya P, Albagi A, Hemmatnia F, Alavi L. Prevalence and treatment outcome of pulmonary and extrapulmonary pediatric tuberculosis in southwestern Iran. Caspian J Intern Med. 2015 Fall;6(4):213-9. PubMed PMID: 26644895; PubMed Central PMCID: PMC4649270.[PubMed]