A Retrospective Cohort Study of Treatment Outcome among HIV positive and HIV negative TB patients in Chandigarh, India


  • Shveta Saini
  • Mukhmohit Singh
  • Anil Garg


Background: Tuberculosis (TB) and the HIV epidemics have been well known previously but now these are emerging as a combined epidemic to pose new public health challenges. TB is the most common opportunistic infection found among HIV positive individuals. Aims & Objective: To find the prevalence of HIV infection among the TB patients diagnosed and put on treatment under RNTCP. 2. To assess their treatment outcomes in Chandigarh. Material & Methods: The present study was designed as a retrospective cohort study among the adult population (>18 years) in Chandigarh from April 2012 - March 2014. All the TB patients registered for treatment at the 17 DMCs of Chandigarh, during this period were taken as the study population. The treatment outcome among TB-HIV co-infected patients was compared with those having only Tuberculosis. Results: From 1st April 2012 - 31st March 2013, a total of 3,551 patients were registered under RNTCP for treatment of tuberculosis. Among the total patients put on DOTS (3,551), 63.2% (2,246) were males and 36.7% (1,305) were females.  A total of 3,516 TB patients had their blood tested for HIV. Out of these patients, 88 (2.47%) were tested positive for HIV. HIV positive status was also found to be significantly associated with occurrence of extra pulmonary tuberculosis (X2= 17.42; df 2; p 0.0001). Category – II treatment was found to be slightly more among the HIV positive TB patients as compared to the HIV negative patients. From the total sample, 2.19% (78) patients were later diagnosed as having drug resistant tuberculosis with only one (01) patient being co-infected with HIV. Out of all the TB-HIV co-infected patients, 29.55% were declared cured at the end of the treatment. A total of 63.64% of co-infected patients had completed their treatment. Death as an outcome was significantly associated with HIV positive status (1.14%) as compared to HIV negative patients. Conclusion: Integration of TB-HIV collaborative activities at every level will strengthen our battle to control TB and HIV globally.


Download data is not yet available.




How to Cite

Saini S, Singh M, Garg A. A Retrospective Cohort Study of Treatment Outcome among HIV positive and HIV negative TB patients in Chandigarh, India. Indian J Community Health [Internet]. 2016 Jun. 30 [cited 2021 Oct. 27];28(2):145-50. Available from: https://iapsmupuk.org/journal/index.php/IJCH/article/view/665



Original Article